Medicines and Related Substances Act, 1965
R 385
Occupational Health and Safety Act, 1993 (Act No. 85 of 1993)RegulationsRegulations for Hazardous Chemical Agents, 2020AnnexuresAnnexure 3 : Hazardous Chemical Agent GuidelinesGuidance on medical surveillance and biological monitoringBiological monitoringObjectives and uses of biological exposure monitoring |
28. | The main objective of biological monitoring is to provide a complementary technique to air monitoring when air sampling techniques alone may not give a reliable indication of exposure. Hence, it may be particularly useful in the following ways: |
(a) | to detect and determine absorption via the skin or gastrointestinal system, in addition to that by inhalation; |
(b) | to test the efficacy of personal protective equipment and monitor work practices; |
(c) | to compliment air monitoring in circumstances when work practices are not normal, such as abnormally long or variable working hours or very strenuous work (high breathing rates = increased chemical intake); |
(d) | to detect non-occupational exposures; |
(e) | to assess total body burden; |
(f) | to reconstruct past exposure in the absence of other exposure measurements for chemicals with long half-lives; and |
(g) | to assess the effectiveness of medical removal procedures when indicated for certain chemicals (e.g. arsenic). |